About Cellenkos

Cellenkos® was founded in 2016 with the licensing of a proprietary umbilical cord blood T-Regulatory (Tregs) cell therapy platform from MD Anderson Cancer Center and funded by Golden Meditech Holdings Ltd, a Hong Kong-based integrated healthcare enterprise. Being derived from umbilical cord blood, cellenkos’ Tregs are naïve, bonafide suppressor cells that resolve inflammation through multiple direct and indirect interactions. Cellenkos is dedicated to the development and commercialization of the allogeneic, off-the-shelf cell based products for the treatment of various inflammatory diseases and autoimmune disorders, in diverse therapy areas.


Management Team

Simrit Parmar, MD

Founder

Dr Simrit Parmar is Tenured Associate Professor in the department of Lymphoma and Myeloma Experimental Therapeutics at MD Anderson Cancer Center, Houston, Texas. Dr Parmar is the principal investigator of research laboratory focused on cord blood derived regulatory T cells including their isolation and ex-vivo expansion for generating clinically relevant dose for their application in autoimmune diseases and inflammatory disorders. She has published her work in peer reviewed journals and her research has been translated into a pilot study of 3rd party cord blood regulatory T cells for prevention of graft versus host disease, where she serves as the principal investigator. Her research has been funded by peer reviewed grants. She was also the proud recipient of the inaugural R. Lee Clark Fellowship award. In addition, she is actively involved with the global academic program as well as MD Anderson Cancer Network program. Dr Parmar is one of the founding members of the Asia Pacific Hematology Consortium that focuses on advancing the field of hematology oncology through continued education, collaboration and fostering innovations. She chairs the radiation injury treatment network (RITN) committee at MD Anderson Cancer Center. Dr Parmar received her hematology / oncology fellowship training at Northwestern University and bone marrow transplant fellowship at MD Anderson Cancer Center.

Tara Sadeghi

Executive Vice President and Head of Manufacturing

Tara Sadeghi brings with her over 25 years experience in clinical research and drug development, regulatory and quality management, and executive leadership. Prior to joining Cellenkos, Inc., Ms. Sadeghi served as Director of Clinical Operations at Bio-Path Holdings, Inc., Assistant Director of Cord Blood Bank Regulatory and Quality Assurance at The University of Texas MD Anderson Cancer Center, and GMP Administrator at Baylor College of Medicine, Center for Cell and Gene Therapy (CAGT).

Jackie Leong

Chairman and Chief Financial Officer

Mr Kim Chuan Leong, also known as Jackie, has been the Chief Financial Officer at FunTalk China Holdings Limited (Formerly Pypo China Holdings Ltd.) since July 2009, and also serves as its Principal Accounting Officer. Mr Leong served as a Vice President and the Chief Financial Officer of FunTalk PRC since August 2008. Mr Leong serves as Chief Financial Officer of Middle Kingdom Alliance Corp. Mr Leong served as a Director and Acting Chief Financial Controller of China Healthcare Inc., the largest Chinese medicine retail chain in the United Kingdom and Republic of Ireland, from August 2007 to July 2008, and Vice President of the Business Development Division at Golden Meditech Holdings Limited, a Hong Kong Stock Exchange listed company, or Golden Meditech, from December 2006 to July 2007. He was a Senior Manager of the Audit Department at KPMG Hong Kong, from April 2004 to November 2006 and a Manager of the Assurance Department of KPMG Singapore, from April 2001 to March 2003. Mr Leong obtained a diploma in financial accounting from Tunku Abdul Rahman College in Malaysia, and is a fellowship member of the Association of Chartered Certified Accountants.

Paul Brooke

Board Director

Paul A. Brooke has served as a member of our Board of Directors since December 2020. Mr. Brooke has also served as the Chairman of Board of Caelum Biosciences which was recently acquired by AstraZeneca's Alexion for US $500 million as of Sept 30, 2021. He was a founder and managing partner of venBio, LLC, a pharmaceutical investment company, from which he retired at the end of 2016. Mr. Brooke was Chairman of the Board of Directors of Alsius Corporation, a medical device company, from June 2007 through its sale in May 2009, and was the Chairman and Chief Executive Officer of a predecessor company from April 2005 to June 2007. Mr. Brooke has been the Managing Member of PMSV Holdings, LLC, a private investment firm, since 1993. He also served as a Senior Advisor to Morgan Stanley & Co. Incorporated from April 2000 to December 2009, and was a Venture Partner at MPM Capital, a venture capital firm specializing in the healthcare industry, from 1997 through 2006. From April 1999 through May 2000, Mr. Brooke served as a Managing Director at Tiger Management LLC. He was a Managing Director and the Global Head of Healthcare Research and Strategy at Morgan Stanley & Co. from 1983 to April 1999. Mr. Brooke is also a director of several privately held companies.


Research partner

The University of Texas MD Anderson Cancer Center in Houston ranks as one of the world's most respected centers focused on cancer patient care, research, education and prevention. It is one of only 41 comprehensive cancer centers designated by the National Cancer Institute (NCI). For the past 25 years, MD Anderson has ranked as one of the nation's top two cancer centers in U.S. News & World Report's annual "Best Hospitals" survey. It receives a cancer center support grant from the NCI of the National Institutes of Health (P30 CA016672).

MD Anderson Cancer Center and Cellenkos collaboration will support the T-REG Program, led by Dr Simrit Parmar.

ASD: AUTISM SPECTRUM DISORDER

AD: ALZHEIMER’S DISEASE

MS: MULTIPLE SCLEROSIS

IBD: INFLAMMATORY BOWEL DISEASE

GVDH: GRAFT VS HOST DISEASE

Ic treg program

AA: APLASTIC ANEMIA

SLE: SYSTEMIC LUPUS ERYTHEMATOSIS

RA: RHEUMATOID ARTHRITIS

T1D: TYPE 1 DIABETES


Our Investor

Golden Meditech Holdings Limited is China's leading integrated-healthcare enterprise. Golden Meditech is a first-mover in China, having established dominant positions in several markets including the medical devices market and the hospital management market in the healthcare industry, thanks to its strengths in innovation and market expertise and the ability to capture emerging market opportunities. Going forward, the Group will continue to pursue a leading position in China's healthcare industry both through organic growth and strategic expansion.

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